10-METHYLPHENOTHIAZINE

CAS No.：1207-72-3

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

View the full Disclaimer

Other grades of this product :

10-METHYLPHENOTHIAZINE Basic information

Product Name:	10-METHYLPHENOTHIAZINE
Synonyms:	N-METHYLPHENOTHIAZINE;10-methyl-10h-phenothiazin;10-Methyl-10H-phenothiazine;9,10-Dibenzoisothiazine, 10-methyl-;Phenothiazide methyl derivative;Phenothiazine, 10-methyl-;AKOS 93806;2 - Methyl Phenothiazine
CAS:	1207-72-3
MF:	C13H11NS
MW:	213.3
EINECS:	214-896-8
Product Categories:	Thioxanthones;Organic Photoinitiators;Polymerization Initiators
Mol File:	1207-72-3.mol

10-METHYLPHENOTHIAZINE Chemical Properties

Melting point	99-101 °C (lit.)
Boiling point	341.6±12.0 °C(Predicted)
density	1.1168 (rough estimate)
refractive index	1.5700 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	powder to crystal
pka	0.56±0.20(Predicted)
color	White to Light yellow
Water Solubility	Insoluble in water.
λmax	310nm(CHCl3)(lit.)
InChIKey	QXBUYALKJGBACG-UHFFFAOYSA-N
CAS DataBase Reference	1207-72-3(CAS DataBase Reference)
EPA Substance Registry System	10H-Phenothiazine, 10-methyl- (1207-72-3)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
TSCA	Yes

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

10-METHYLPHENOTHIAZINE Usage And Synthesis

Chemical Properties	slightly yellow to pale green crystalline powder
Uses	They are used in pharmaceutical manufacturing especially antipsychotic drugs. Also used as a stabilizer against polymerization of acrylates.
Purification Methods	Recrystallise it (three times) from EtOH to give the -form (prisms). Recrystallisation from EtOH/*benzene gives the .-form (needles). It has also been purified by vacuum sublimation and is carefulmax 255nm (log 4.60) (pH 6.3) and 255nm in hexane. [Cymerman-Craig & Warburton Aust J Chem 9 294 1956, Beilstein 27 II 33, 27 III/IV 1215.]

10-METHYLPHENOTHIAZINE Preparation Products And Raw materials

Raw materials

Pyridine, 2-methyl-3,6-diphenyl--->tert-butyl 2-(10H-phenothiazin-10-yl)acetate-->1-PHENYLNAPHTHALENE-->10H-Phenothiazine, 10-methyl-, 5-oxide-->PHENOTHIAZINE-10-ACETIC ACID-->Thiophene, 2-bromo-5-[(ethylsulfonyl)methyl]--->Phenylacetylene-->1,3,5-trioxane-->Hydrochloric acid-->4-Ethynyltoluene-->Phenothiazine

Welcome！

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
+86-23-6139-8061 +86-13650506873
danny@chemdad.com sales@chemdad.com
www.chemdad.com
WhatsApp +86-13650506873