Other grades of this product :
| Tygacil Basic information |
| Product Name: | Tygacil | | Synonyms: | 9-t-Butylglycylamido-minocycline hydrate;TBG-MINO;Tigecyclin;Tigecycline hydrate;(4S,4aS,5aR,12aR)-9-[[2-(tert-butylamino)acetyl]amino]-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide,hydrate;GAR-936 hydrate | | CAS: | 1229002-07-6 | | MF: | C29H41N5O9 | | MW: | 603.67 | | EINECS: | | Product Categories: | | Mol File: | 1229002-07-6.mol |
| Tygacil Chemical Properties |
| storage temp. | 2-8°C | | solubility | DMSO: ≥3mg/mL (warmed) | | form | powder | | color | off-white to yellow-brown | | optical activity | [α]/D -160 to 170°, c = 0.15 in methanol |
| Tygacil Usage And Synthesis |
| Uses | Tigecycline hydrate, a glycylcycline antibiotic, used to treat infection by drug resistant bacteria such as Staphylococcus aureus (Staph aureus) and Acinetobacter baumannii. | | General Description | Tigecycline is used to treat complicated skin and skin structure infections (cSSSI) and complicated intraabdominal infections. | | Biochem/physiol Actions | Tigecycline is a broad spectrum glycylcycline antibiotic. Tigecycline is bacteriostatic, that inhibits protein synthesis by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation. Tigecycline is active against resistant strains of gram-positive and gram-negative bacteria, avoiding the two most common mechanisms of resistance to the tetracycline antimicrobials: tetracycline efflux pump proteins and ribosomal protection proteins. |
| Tygacil Preparation Products And Raw materials |
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