2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid

CAS No.：123021-85-2

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2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid Basic information

Product Name:	2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid
Synonyms:	2-(4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)acetic acid;2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid;GPR35 Agonist, Compound 10;GPR35 Agonist, Compound 10 >=98% (HPLC);2-{4-[(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]p henoxy}acetic acid
CAS:	123021-85-2
MF:	C12H9NO5S
MW:	279.27
EINECS:
Product Categories:
Mol File:	123021-85-2.mol

2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid Chemical Properties

storage temp.	2-8°C
solubility	DMSO: ≥5mg/mL at ~60°C
form	powder
color	white to tan

Safety Information

Hazard Codes	Xi
Risk Statements	36
Safety Statements	26
WGK Germany	3

MSDS Information

2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid Usage And Synthesis

Uses	GPR35 Agonist, Compound 10, may be used in GPR35-mediated cell signaling studies.
Biochem/physiol Actions	GPR35 agonist Compound 10 is a GPR35 agonist the binds with higher affinity than other known agonists, such as kynurenic acid and zaprinast. Compound 10 was more potent than zaniprast (pEC50 = 5.3 vs 4.18) for recombinantly expressed human GPR35, and unlike zaprinast, is equipotent for human and rat GPR35

2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid Preparation Products And Raw materials

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