COELENTERAZINE HCP

COELENTERAZINE HCP
  • CAS No.:123437-32-1

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
COELENTERAZINE HCP Basic information
Product Name:COELENTERAZINE HCP
Synonyms:IMIDAZO[1,2-A]PYRAZIN-3(7H)-ONE, 8-(CYCLOPENTYLMETHYL)-6-(4-HYDROXYPHENYL)-2-(PHENYLMETHYL)-;CLZ-HCP;CLZN-HCP;COELENTERAZINE HCP;COELENTERAZINE-HCP, SYNTHETIC;2-BENZYL-6-(P-HYDROXYPHENYL)-8-CYCLOPENTYLMETHYLIMIDAZO[1,2-A]PYRAZIN-3-(7H)-ONE;CLZN hcp [Coelenterazine hcp];Coelenterazine hcp *CAS 123437-32-1*
CAS:123437-32-1
MF:C25H25N3O2
MW:399.48
EINECS:
Product Categories:Heterocycle;Imidazo[1,2-a]pyrazin-3(7H)-one
Mol File:123437-32-1.mol
COELENTERAZINE HCP Chemical Properties
Melting point >200℃
storage temp. -20°C
solubility Soluble in ethanol, methanol
form solid
color Yellow
λmax433nm
Biological ApplicationsCalcium indicator; assaying luminescent enzyme; measuring luciferase activity; as a substrate for luciferase; screening HIV-1 protease inhibitors; bioluminescence resonance energy transfer (BRET) detection system
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
MSDS Information
COELENTERAZINE HCP Usage And Synthesis
UsesCoelenterazine hcp has been used:
  • as a component of coelenterazine reagent in the reporter assay
  • in the purification of Renilla luciferase-labeled Annexin V
  • in evaluating the activity of aequorin in Escherichia coli
General DescriptionCoelenterazine hcp is a semisynthetic analog of coelenterazine.
Biochem/physiol ActionsCoelenterazine hcp has 190 times higher luminescence intensity than native coelenterazine and a faster response time than native coelenterazine.
COELENTERAZINE HCP Preparation Products And Raw materials

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