Product

(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride

CAS No.：125572-93-2

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(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride Basic information

Product Name:	(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
Synonyms:	(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride;Rotigotine hydrochloride;(6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenolhydrochloride;(S)-6-(propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride;(6S)-;8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]aMino]-;CEXBONHIOKGWNU-NUDVEOEASA-N;rotigotine HCl
CAS:	125572-93-2
MF:	C19H26ClNOS
MW:	351.93
EINECS:	603-080-0
Product Categories:	APIs;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;API
Mol File:	125572-93-2.mol

(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride Chemical Properties

Melting point	114-117°C
density	1.2g/cm3 at 20℃
vapor pressure	0-0Pa at 20-25℃
storage temp.	room temp
solubility	Acetone (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly)
form	solid
color	white to off-white
LogP	3.1 at 20℃ and pH7
Surface tension	72.3mN/m at 1g/L and 20℃

Safety Information

WGK Germany	2
HS Code	2934990002

MSDS Information

(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride Usage And Synthesis

Chemical Properties	White to Off-White Solid
Uses	It is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinson’s disease.
Uses	It is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinson’s disease.
Biochem/physiol Actions	Rotigotine is a dopamine receptor agonist with preference for D3 receptors over D2 and D1. As such, it is an effective anti-Parkinsonian agent. Racemic rotigotine is about 50 times as potent as quinpirole, the gold standard D2 agonist.

(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride Preparation Products And Raw materials

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