HUMAN VEGF165

HUMAN VEGF165
  • CAS No.:127464-60-2
Other grades of this product :
HUMAN VEGF165 Basic information
Product Name:HUMAN VEGF165
Synonyms:mVEGF;Vascular Endothelial Growth Factor from mouse;Vascular Endothelial Growth Factor (aa 207-318) human;VEGF112;Anti-VEGFA antibody produced in goat;MGC70609;MVCD1;VPF
CAS:127464-60-2
MF:NULL
MW:0
EINECS:
Product Categories:monoclonal antibody
Mol File:Mol File
HUMAN VEGF165 Chemical Properties
storage temp. -20°C
form powder
color white
Safety Information
Safety Statements 22-24/25
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
HUMAN VEGF165 Usage And Synthesis
UsesVEGF human has been used as a chemoattractant for HUVECs (human umbilical vein endothelial cells) migration assay.
General DescriptionVEGF (vascular endothelial growth factor) signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human VEGF is a 38.2kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
Biochem/physiol ActionsVEGF (vascular endothelial growth factor) is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intraocular neovascular syndromes. Polymorphism in VEGF at C(-634)G is linked with diabetic retinopathy in type 2 diabetes.
HUMAN VEGF165 Preparation Products And Raw materials

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