Other grades of this product :
| Regramostim Basic information |
| Product Name: | Regramostim | | Synonyms: | Colony-stimulating factor 2 (human clone pcsf-1 protein moiety reduced), glycoform gmc 89-107;Regramostime;Regramostime [inn-french];Regramostimum;Regramostimum [inn-latin];GM-CSF from mouse;pluripoietin-;MGI-1GM | | CAS: | 127757-91-9 | | MF: | | MW: | 0 | | EINECS: | | Product Categories: | | Mol File: | Mol File |
| Regramostim Chemical Properties |
| storage temp. | -20°C | | form | lyophilized | | color | white to off-white |
| Hazard Codes | Xi | | Risk Statements | 36/38 | | Safety Statements | 26 | | WGK Germany | 3 |
| Regramostim Usage And Synthesis |
| Uses | Antineutropenic; hematopoietic stimulant. | | Uses | GM-CSF (granulocyte-macrophage colony-stimulating factor) mouse has been used to check effect of GM-CSF on retinal ganglion cell neurite outgrowth in the retinal explants. | | General Description | GM-CSF (granulocyte-macrophage colony-stimulating factor, also referred to as CSF2) is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. Recombinant murine GM-CSF is a 14.2kDa globular protein consisting of 124 amino acids residues. The human and murine molecules are species-specific and exhibit no cross-species reactivity. | | Biochem/physiol Actions | GM-CSF (granulocyte-macrophage colony-stimulating factor, also referred to as CSF2) is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It enhances neutrophil migration. GM-CSF plays a crucial role in inflammatory and autoimmune diseases. In neutrophils, it promotes the expression of TLR2 (Toll-like receptor) and TLR2-associated interleukin 8 responses, thereby eliminating microbial attack. |
| Regramostim Preparation Products And Raw materials |
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