ARVANIL

ARVANIL
  • CAS No.:128007-31-8
Other grades of this product :
ARVANIL Basic information
Product Name:ARVANIL
Synonyms:N-VANILLYLARACHIDONAMIDE;N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE;11,14-eicosatetraenamide(all-z)-n-((4-hydroxy-3-methoxyphenyl)methyl)-8;14-eicosatetraenamide,n-((4-hydroxy-3-methoxyphenyl)methyl)-(all-z)-11;ARVANIL;(5Z,8Z,11Z,14Z)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-5,8,11,14-Eicosatetraenamide
CAS:128007-31-8
MF:C28H41NO3
MW:439.63
EINECS:
Product Categories:Cannabinoid receptor
Mol File:128007-31-8.mol
ARVANIL Chemical Properties
Fp 14℃
storage temp. -20°C
form liquid
color colorless to pale yellow
Safety Information
RIDADR UN1170 - class 3 - PG 2 - Ethanol
WGK Germany 3
RTECS JX3845000
MSDS Information
ProviderLanguage
SigmaAldrich English
ARVANIL Usage And Synthesis
UsesArvanil is a cannabinoid CB1?and vanilloid TRPV1 (VR) agonist.
Biological ActivityCannabinoid CB 1 and vanilloid TRPV1 (VR1) agonist (K i values are 0.5 and 0.3 μ M respectively). Also inhibits the anandamide transporter (IC 50 = 3.6 μ M). Analgesic, vasodilatory and anti-inflammatory in vivo .
Biochem/physiol ActionsArvanil is an activator of cannabinoid and vanilloid receptors, and a potent inhibitor of anandamide accumulation. Arvanil inhibits growth of astrocytoma xenograft tumors in mice, mimicing the effect of neural precursor cells, that have been shown to kill TRPV1-expressing tumor cells by secreting endovanilloids.
ARVANIL Preparation Products And Raw materials

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