DEHYDRO ARIPIPRAZOLE

DEHYDRO ARIPIPRAZOLE
  • CAS No.:129722-25-4
Other grades of this product :
DEHYDRO ARIPIPRAZOLE Basic information
Product Name:DEHYDRO ARIPIPRAZOLE
Synonyms:DEHYDRO ARIPIPRAZOLE;7-[4-[4-(2,3-Dichlorophenyl)-1-Piperazinyl]Butoxy]-2(1H)-Quinolinone;2(1H)-Quinolinone,7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-;7-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butoxy)quinolin-2(1H)-one;Aripiprazole Related CoMpound G;Aripiprazole USP impurity G(EP impurity E);Dehydro aripiprazole solution;Aripiprazole Related Compound G (25 mg) (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}quinolin-2(1H)-one)
CAS:129722-25-4
MF:C23H25Cl2N3O2
MW:446.37
EINECS:
Product Categories:
Mol File:129722-25-4.mol
DEHYDRO ARIPIPRAZOLE Chemical Properties
Melting point >139oC (dec.)
Boiling point 654.4±55.0 °C(Predicted)
density 1.281±0.06 g/cm3(Predicted)
Fp 349℃
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly, Heated)
form Solid
pka11.22±0.70(Predicted)
color White to Off-White
InChIKeyCDONPRYEWWPREK-UHFFFAOYSA-N
Safety Information
Hazard Codes F,T
Risk Statements 11-23/24/25-39/23/24/25-52/53
Safety Statements 16-36/37-45-61
RIDADR UN 3286 8(6.1)(3) / PGII
WGK Germany 1
HS Code 2933790002
MSDS Information
DEHYDRO ARIPIPRAZOLE Usage And Synthesis
UsesDehydro Aripiprazole (Aripiprazole EP Impurity E; Aripiprazole USP Related Compound G) is an impurity of Aripiprazole (A771000), a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity.
General DescriptionDehydro Aripiprazole is the primary, active metabolite of aripiprazole, marketed as the atypical antipsychotic Abilify? for the treatment of schizophrenia, bipolar disorder, and clinical depression. This new certified solution standard is suitable for use in LC or GC applications including forensic or clinical toxicology analysis and urine drug testing.
DEHYDRO ARIPIPRAZOLE Preparation Products And Raw materials
Raw materialsAripiprazole-->1-(2,3-Dichlorophenyl)-piperazine-->7-Hydroxyquinolinone-->7-(4-BROMOBUTOXY)-QUINOLINE-2(1H)-ONE

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