FMOC-GAMMA-ABU-OH

FMOC-GAMMA-ABU-OH
  • CAS No.:116821-47-7
Other grades of this product :
FMOC-GAMMA-ABU-OH Basic information
Product Name:FMOC-GAMMA-ABU-OH
Synonyms:RARECHEM EM WB 0021;N-(9-FLUORENYLMETHOXYCARBONYL)-GAMMA-AMINOBUTANOIC ACID;N-(9-FLUORENYLMETHOXYCARBONYL)-4-AMINOBUTYRIC ACID;N-(9-FLUORENYLMETHYLOXYCARBONYL)-GAMMA-AMINOBUTYRIC ACID;N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-GAMMA-AMINOBUTYRIC ACID;N-GAMMA-FMOC-GAMMA-AMINOBUTYRIC ACID;N-FMOC-DL-4-AMINO-BUTYRIC ACID;N-γ-Fmoc-γ-aminobutyricacid
CAS:116821-47-7
MF:C19H19NO4
MW:325.36
EINECS:1533716-785-6
Product Categories:Miscellaneous Amino Acids;Amino Acids
Mol File:116821-47-7.mol
FMOC-GAMMA-ABU-OH Chemical Properties
Melting point 172.0 to 176.0 °C
Boiling point 571.9±33.0 °C(Predicted)
density 1.256±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka4.68±0.10(Predicted)
form Powder
color White
Water Solubility Slightly soluble in water.
BRN 7491485
CAS DataBase Reference116821-47-7(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
HS Code 2924 29 70
HazardClass IRRITANT
MSDS Information
ProviderLanguage
SigmaAldrich English
FMOC-GAMMA-ABU-OH Usage And Synthesis
DescriptionFmoc-4-aminobutanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Fmoc-4-aminobutanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Chemical PropertiesWhite powder
Uses4-(Fmoc-amino)butyric acid is used in agrochemical, pharmaceutical and dyestuff field.
FMOC-GAMMA-ABU-OH Preparation Products And Raw materials

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