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| (-)-CATECHIN GALLATE Basic information |
| (-)-CATECHIN GALLATE Chemical Properties |
| Melting point | 248-251 °C (decomp) | | Boiling point | 861.7±65.0 °C(Predicted) | | density | 1.80±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO (Slightly), Ethanol (Slightly) | | form | Solid | | pka | 7.75±0.25(Predicted) | | color | Pale Yellow to Light Red | | InChIKey | LSHVYAFMTMFKBA-CTNGQTDRSA-N |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HS Code | 29329990 |
| (-)-CATECHIN GALLATE Usage And Synthesis |
| Uses | A major component of green tea, is a dual phosphoinositide-3-kinase/mTOR inhibitor. | | Uses | (?)-Catechin gallate has been used:- to examine the potency of catechins containing galloyl moiety in inhibiting the activity of human immunodeficiency virus-1 (HIV-1)integrase
- to analyze the anti-oxidant and anti-viral properties of Pseudopiptadenia contorta and the commercial quebracho extracts in a herpes simplex virus type 1 strain, resistant to acyclovir
- to study the effects of polyphenols on the biochemistry of human spermatozoa and the associated limitations of their use in gamete preservation
| | General Description | (?)-Catechin gallate belongs to a class of polyphenol compounds that are formed when catechins in green tea undergo epimerization on heat treatment. It is a naturally occurring flavanol catechin having a galloyl moiety. | | Biochem/physiol Actions | Antioxidant constituent of green tea. At μM concentrations, it inhibits VEGF-induced tyrosine phosphorylation. It also inhibits aromatase activity, an enzyme that converts androgens to estrogen and is thought to play a role in the etiology of breast cancer. |
| (-)-CATECHIN GALLATE Preparation Products And Raw materials |
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