(-)-CATECHIN GALLATE

(-)-CATECHIN GALLATE
  • CAS No.:130405-40-2

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
(-)-CATECHIN GALLATE Basic information
Product Name:(-)-CATECHIN GALLATE
Synonyms:Catechin gallate CG (-)-Catechin gallate;(-)-Catechin 3-O-gallate);(-)-Catechin gallate ((-)-Catechin 3-gallate;(-)-Catechin gallate(CG);Anti-HCG β, C-Terminal antibody produced in rabbit;Choriogonadotropin subunit β;Chorionic gonadotrophin chain β;ANTI-CG antibody produced in mouse
CAS:130405-40-2
MF:C22H18O10
MW:442.37
EINECS:
Product Categories:phytochemical;reference standards from Chinese medicinal herbs (TCM).;Aromatics;chemical reagent;pharmaceutical intermediate;standardized herbal extract;Catechins & Tannins;Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:130405-40-2.mol
(-)-CATECHIN GALLATE Chemical Properties
Melting point 248-251 °C (decomp)
Boiling point 861.7±65.0 °C(Predicted)
density 1.80±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO (Slightly), Ethanol (Slightly)
form Solid
pka7.75±0.25(Predicted)
color Pale Yellow to Light Red
InChIKeyLSHVYAFMTMFKBA-CTNGQTDRSA-N
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
HS Code 29329990
MSDS Information
(-)-CATECHIN GALLATE Usage And Synthesis
UsesA major component of green tea, is a dual phosphoinositide-3-kinase/mTOR inhibitor.
Uses(?)-Catechin gallate has been used:
  • to examine the potency of catechins containing galloyl moiety in inhibiting the activity of human immunodeficiency virus-1 (HIV-1)integrase
  • to analyze the anti-oxidant and anti-viral properties of Pseudopiptadenia contorta and the commercial quebracho extracts in a herpes simplex virus type 1 strain, resistant to acyclovir
  • to study the effects of polyphenols on the biochemistry of human spermatozoa and the associated limitations of their use in gamete preservation
General Description(?)-Catechin gallate belongs to a class of polyphenol compounds that are formed when catechins in green tea undergo epimerization on heat treatment. It is a naturally occurring flavanol catechin having a galloyl moiety.
Biochem/physiol ActionsAntioxidant constituent of green tea. At μM concentrations, it inhibits VEGF-induced tyrosine phosphorylation. It also inhibits aromatase activity, an enzyme that converts androgens to estrogen and is thought to play a role in the etiology of breast cancer.
(-)-CATECHIN GALLATE Preparation Products And Raw materials

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