Other grades of this product :
| Chlorobutanol Basic information |
| Product Name: | Chlorobutanol | | Synonyms: | β,β,β-trichloro-tert-butyl;Chlorobutanol(0.5H2O);Butene chlorohydrin;Chlorobutanol;Chlorobutanol CRS;(0.5 H2O);Trichlorot-butyl alcohol hemihydrate | | CAS: | 1320-66-7 | | MF: | C4H7Cl3O | | MW: | 177.46 | | EINECS: | 215-305-6 | | Product Categories: | | Mol File: | 1320-66-7.mol |
| Chlorobutanol Chemical Properties |
| Chlorobutanol Usage And Synthesis |
| Chemical Properties | Crystalline solid with a camphor-like odorand taste; sublimes; mp 97°C (206°F)(hemihydrate 78°C (172°F)); bp 167°C(332°F); soluble in water and organic solvents.. | | Uses | Pharmaceutic
aid (antimicrobial agent). | | Uses | Chlorobutanol is used as a plasticizer forcellulose esters, as a preservative for hypodermic solutions, and in veterinary medicineas a mild sedative and antiseptic. | | Brand name | Chloretone (Parke-Davis). | | Health Hazard | Chlorobutanol exhibited moderate toxicity intest animals. A lethal dose by oral intake indogs and rabbits were 238 and 213 mg/kg,respectively (NIOSH 1986). The toxic symptoms are not reported. This compound isa mild skin and eye irritant and may bemutagenic. | | Clinical Use | 1,1,1-Trichloro-2-methyl-2-propanol is a white crystallinesolid with a camphorlike aroma. It occurs in an anhydrousform and a hemihydrate form, both of which sublime at roomtemperature and pressure. Chlorobutanol is slightly soluble inwater and soluble in alcohol and in organic solvents.Chlorobutanol is used as a bacteriostatic agent in pharmaceuticalsfor injection, ophthalmic use, and intranasal administration.It is unstable when heated in aqueous solution, especially at pH greater than 7. Under these conditions,chlorobutanol undergoes elimination. Solutions with a pHof approximately 5 are reasonably stable at 25°C.Chlorobutanol is stable in oils and organic solvents. | | Waste Disposal | A suitable method of destruction of chlorobu tanol is the burning of its solution in a com bustible solvent in a chemical incinerator. |
| Chlorobutanol Preparation Products And Raw materials |
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