Product

4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE

CAS No.：133060-80-7

Other grades of this product :

4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE Basic information

Product Name:	4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE
Synonyms:	ZD 7288;4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE;N-Ethyl-1,6-dihydro-1,2-dimethyl-6-(methylimino)-N-phenyl-4-Pyrimidinamine;ZD7288 hydrate;4-(N-Ethyl-N-phenylamino)-1,2 dimethyl-6-(methylamino) pyrimidinium chloride;4-Pyrimidinamine, N-ethyl-1,6-dihydro-1,2-dimethyl-6-(methylimino)-N-phenyl-;ZD7288 hydrate >=98% (HPLC)
CAS:	133060-80-7
MF:	C15H20N4
MW:	256.35
EINECS:
Product Categories:	Ion transporter and other ion channel
Mol File:	133060-80-7.mol

4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE Chemical Properties

Boiling point	359.9±52.0 °C(Predicted)
density	1.04±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: soluble10mg/mL, clear
pka	11.97±0.70(Predicted)
form	powder
color	white to beige

Safety Information

WGK Germany

MSDS Information

4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE Usage And Synthesis

Uses	ZD7288 hydrate has been used as?I_h?blocker to study its effect on neocortical tissue. It has been used as hyperpolarization-activated and cyclic nucleotide-gated (HCN)-channel blocker to test the involvement of HCN channels in the phototransduction pathway.
Biochem/physiol Actions	Selective blocker of cation channel Ih; If blocker and sino-atrial node function modulator, blocks hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels.

4-ETHYLPHENYLAMINO-1,2-DIMETHYL-6-METHYLAMINOPYRIMIDINIUM CHLORIDE Preparation Products And Raw materials

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