Product

(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL

CAS No.：134234-12-1

Other grades of this product :

(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL Basic information

Product Name:	(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL
Synonyms:	1-((1S,2S);-1-Hydroxy-1-(4-hydroxyphenyl);propan-2-yl);(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL;CP 101606;1-[(1S,2S)-2-Hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]-4-phenylpiperidin-4-ol;(1s,2s)-1-[4-[ hydroxylphenyl]- 2- ( 4-hydroxy-4-pheny1piperidino)-1- propanol;1-((1S,2S)-1-Hydroxy-1-(4-hydroxyphenyl)propan-2-yl)-4-phenylpiperidin-4-ol
CAS:	134234-12-1
MF:	C20H25NO3
MW:	327.42
EINECS:
Product Categories:
Mol File:	134234-12-1.mol

(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL Chemical Properties

Boiling point	534.4±50.0 °C(Predicted)
density	1.228
storage temp.	2-8°C
solubility	DMSO: ≥35mg/mL
pka	9.99±0.26(Predicted)
form	powder
color	white to tan
optical activity	[α]/D +50 to +60° (c=1, MeOH)

Safety Information

Hazard Codes	T,N
Risk Statements	25-36-50
Safety Statements	26-45-61
RIDADR	2811
WGK Germany	3
HazardClass	IRRITANT
PackingGroup	Ⅲ

MSDS Information

(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL Usage And Synthesis

Uses	Traxoprodil (CP101,606) is a potent and selective NMDA antagonist and protect hippocampal neurons with an IC50 of 10 nM.
Uses	CP-101,606 has been used as a N-methyl-D-aspartate (NMDA)?receptor antagonist to study its role in recovery of spinal cord injuries.
Brand name	Traxoprodil is INN.
General Description	CP-101,606 (Traxoprodil) is a substituted 4-phenylpiperidine and is localized in the fore brain neurons.
Biochem/physiol Actions	Traxoprodil (CP-101,606) is a potent noncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptors, selective for the NR2B subunit. It has been shown to be neuroprotective in animal models of brain injury and stroke.

(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL Preparation Products And Raw materials

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