METHYL PHENYL SULFOXIDE

METHYL PHENYL SULFOXIDE
  • CAS No.:1193-82-4

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
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METHYL PHENYL SULFOXIDE Basic information
Product Name:METHYL PHENYL SULFOXIDE
Synonyms:(Methylsulfinyl)benzene;Phenyl methyl sulfoxide;Sulfoxide, methyl phenyl;Thioanisole S-oxide;METHYL PHENYL SULPHOXIDE;METHYL PHENYL SULFOXIDE;(methylsulphinyl)benzene;METHYL PHENYL SULFOXIDE, 97+%
CAS:1193-82-4
MF:C7H8OS
MW:140.2
EINECS:214-781-2
Product Categories:Sulfur Compounds;Sulfur Compounds (for Synthesis);Synthetic Organic Chemistry;Organic Building Blocks;Sulfoxides
Mol File:1193-82-4.mol
METHYL PHENYL SULFOXIDE Chemical Properties
Melting point 26-29 °C (lit.)
Boiling point 139-140 °C/14 mmHg (lit.)
density 1.1182 (rough estimate)
refractive index n20/D 1.5775(lit.)
Fp 187 °F
storage temp. 2-8°C
form Crystalline Low Melting Mass
color White
Sensitive Hygroscopic
BRN 1904976
CAS DataBase Reference1193-82-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 37/38-41
Safety Statements 22-24/25-39-26
WGK Germany 3
HS Code 29309090
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
METHYL PHENYL SULFOXIDE Usage And Synthesis
Chemical Propertieswhite crystalline low melting mass
UsesMethyl phenyl sulfoxide has been used in the synthesis of:
  • isotopically labelled 1, 3-dithiane, a useful labeled synthon
  • nelfinavir, potent HIV-protease inhibitor
  • sulfoximines and in studies on solvent-water partitioning
Synthesis Reference(s)The Journal of Organic Chemistry, 50, p. 2847, 1985 DOI: 10.1021/jo00216a007Tetrahedron Letters, 22, p. 4591, 1981 DOI: 10.1016/S0040-4039(01)82989-0
General Description(R)-methyl phenyl sulfoxide is an important pharmaceutical intermediate.
METHYL PHENYL SULFOXIDE Preparation Products And Raw materials
Raw materials2-METHYL-N-(PHENYLMETHYLENE)-2-PROPYLAMINE-->N-TERT-BUTYL-ALPHA-PHENYLNITRONE-->Methyl phenyl sulfone-->Thioanisole
Preparation ProductsMETHYL BENZENESULFINATE

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