4,5,6,7-TETRAHYDROINDOLE

4,5,6,7-TETRAHYDROINDOLE
  • CAS No.:13618-91-2
Other grades of this product :
4,5,6,7-TETRAHYDROINDOLE Basic information
Product Name:4,5,6,7-TETRAHYDROINDOLE
Synonyms:4,5,6,7-TETRAHYDROINDOLE;4,5,6,7-TETRAHYDRO-1H-INDOLE;4,5,6,7-TETRAHYDROINDOLE 98+%;1H-Indole, 4,5,6,7-tetrahydro-;2,3-Tetramethylenepyrrole;Cyclohex[b]pyrrole;NSC 122455;4,5,6,7-Tetrahydroindole 98%
CAS:13618-91-2
MF:C8H11N
MW:121.18
EINECS:
Product Categories:Building Blocks;Heterocyclic Building Blocks;Indoles
Mol File:13618-91-2.mol
4,5,6,7-TETRAHYDROINDOLE Chemical Properties
Melting point 53-57 °C(lit.)
storage temp. 2-8°C
BRN 108853
InChIKeyKQBVVLOYXDVATK-UHFFFAOYSA-N
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39
WGK Germany 3
1-10
HS Code 2933998090
MSDS Information
ProviderLanguage
SigmaAldrich English
4,5,6,7-TETRAHYDROINDOLE Usage And Synthesis
Uses4,5,6,7-Tetrahydro-1H-indole is used in preparation of chiral tetraaryl-substituted Methane. Also, used in preparation of 4-substituted Phenylamidine derivatives used for controlling phytopathogenic microorganisms.
Uses4,5,6,7-Tetrahydroindole was used as reactant in:
  • synthesis of ethyl 3-(4,5,6,7-tetrahydroindol-2-yl)-2-propynoate
  • preparation of BODIPY dyes
  • N-alkylation with chloromethyloxirane
  • preparation of hydroindolepropynoate by chemo- and regioselective solvent-free ethynylation
  • palladium- and copper-free cross-coupling of halopropynoates
  • preparation of carbonylalkenyl indoles via coupling with dicarbonyl compounds
  • 1:2 annelation of 4,5,6,7-tetrahydroindole with 1-benzoyl-2-phenylacetylene
General Description4,5,6,7-Tetrahydroindoles, due to their easy aromatization, are good intermediates to synthesize indoles. 4,5,6,7-Tetrahydroindole on condensation with cyanoacetate leads to 1-ethylthio-2-cyano-4,5,6,7-tetrahydrocyclohexa-[c]-3H-pyrrolizin-3-one.
4,5,6,7-TETRAHYDROINDOLE Preparation Products And Raw materials

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