DTBA

DTBA
  • CAS No.:1363376-98-0

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
DTBA Basic information
Product Name:DTBA
Synonyms:2,4-Dihydroxy-3,5,6-trimethylbenzoic acid;DTBA;USF-406B;(2S)-2-Amino-1,4-dimercaptobutane hydrochloride;(S)-2-Aminobutane-1,4-dithiol hydrochloride;(S)-2-Aminobutane-1,4-dithiol hydrochloride 99% (titration);Dithiobutylamine Hydrochloride
CAS:1363376-98-0
MF:C4H12ClNS2
MW:173.72778
EINECS:
Product Categories:
Mol File:1363376-98-0.mol
DTBA Chemical Properties
Melting point 210-225°C
storage temp. 2-8°C
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 26
WGK Germany 3
MSDS Information
DTBA Usage And Synthesis
UsesDithiobutylamine is a dithiol that can be synthesized from L-aspartic acid (A790021). Dithiobutylamine is a potent and versatile disulfide-reducing agent that is capable of reducing the enzyme papain, which has a relatively anionic active site, 14 times as fast as DTT (D494285) could.
UsesDithiobutylamine or DTBA is a new biological reducing reagent with enhanced properties over other commonly used reagents. DTBA was shown to reduce small molecule disulfides 3-5x faster than DTT and was able to reduce (activate) the cysteine dependent protease papain 14x faster than DTT. In addition, due to the presence of the primary amine group, removal of DTBA from mixtures after use is simplified and can be achieved using cation exchange resin.
DTBA Preparation Products And Raw materials

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