Product

(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol

CAS No.：1382486-90-9

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(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol Basic information

Product Name:	(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol
Synonyms:	(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol;(R)-FTY720-OME
CAS:	1382486-90-9
MF:	C20H35NO2
MW:	321.4974
EINECS:
Product Categories:
Mol File:	1382486-90-9.mol

(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol Chemical Properties

storage temp.

-20°C

Safety Information

MSDS Information

(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol Usage And Synthesis

General Description	(R)-FTY720-OMe is a structural analogue of FTY720 which acts as a specific competitive inhibitor of sphingosine kinase 2 (SK2). Furthermore, (R)-FTY720-OMe does not inhibit sphingosine kinase 1 (SK1) activity.
Biochem/physiol Actions	(R)-FTY720-OMe helps to block DNA synthesis and actin rearrangement induced by sphingosine 1-phosphate (S1P) in MCF-7 breast cancer cells. It can also reduce sphingosine kinase 2 (SK2) expression and prevent DNA synthesis in HEK 293 cells. (R)-FTY720-OMe has anti-breast cancer potential.

(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol Preparation Products And Raw materials

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