Other grades of this product :
| CL 316243 Basic information |
| Product Name: | CL 316243 | | Synonyms: | CL 316243 disodium
(CL316243 disodium);Disodium 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate hydrate;CL-316243 sodium;CL 316243;COLLAGEN FROM HUMAN LUNG;Disodium 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate;CL 316,243 hydrate | | CAS: | 138908-40-4 | | MF: | C20H18ClNO7.2Na | | MW: | 465.795 | | EINECS: | | Product Categories: | | Mol File: | 138908-40-4.mol |
| CL 316243 Chemical Properties |
| storage temp. | room temp | | solubility | H2O: >10 mg/mL | | form | solid | | color | white |
| CL 316243 Usage And Synthesis |
| Uses | CL 316243 Disodium Salt is a potent and highly selective β3-adrenoceptor agonist. | | Uses | CL 316,243 hydrate has been used:- as a β-agonists to inject mice and study its effect on the expression of mammalian major facilitator superfamily domain-containing protein (Mfsd2a)
- as an adrenergic agonist to stimulate adrenergic response in order to study the metabolic activity of brown, beige and white adipose tissues in mice
- as a β3-adrenergic agonist to inject mice for in vivo lipolytic challenge
| | Hazard | A poison.
| | Biochem/physiol Actions | β Adrenoceptor is expressed in a number of tissues such as heart, adipose tissue, colon and other tissues. It is associated with many different biological functions. β Adrenoceptor fills in as an objective for treating type 2 diabetes, heart failure, cachexia, obesity, metabolic disorder, issues related with bladder, colon and malignant tumor growth. Depression and anxiety can also be treated via β adrenoceptor. CL 316,243 is known to have antidiabetic action via β adrenoceptor. It is a potent stimulator of lipolysis. It also activates β3- adrenoceptors on neurons in hypothalamic areas that are important in the central regulation of appetite. |
| CL 316243 Preparation Products And Raw materials |
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