Other grades of this product :
| ZM 241385 Basic information |
| Product Name: | ZM 241385 | | Synonyms: | 4-(2-[7-AMINO-2-(2-FURYL)[1,2,4]TRIAZOLO[2,3-A][1,3,5]TRIAZIN-5-YLAMINO]ETHYL)PHENO;Phenol, 4-[2-[[7-amino-2-(2-furanyl)[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino]ethyl]-;4-(2-[7-AMINO-2-(2-FURYL)[1,2,4]TRIAZOLO[2,3-A][1,3,5]TRIAZIN-5-YLAMINO]ETHYL)PHENOL;ZM 241385;4-(2-(7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-ylamino)ethyl)phenol;CS-2353;ZM 241385; ZM241385; ZM-241385;7-amino-2-(furan-2-yl)-5-[2-(4-hydroxyphenyl)ethyl]amino-[1,2,4]triazolo[1,5-a][1,3,5]triazine | | CAS: | 139180-30-6 | | MF: | C16H15N7O2 | | MW: | 337.34 | | EINECS: | | Product Categories: | Adenosine | | Mol File: | 139180-30-6.mol |
| ZM 241385 Chemical Properties |
| density | 1.59±0.1 g/cm3(Predicted) | | storage temp. | room temp | | solubility | DMSO: >15mg/mL | | pka | 10.03±0.15(Predicted) | | form | powder | | color | white to tan |
| Hazard Codes | T | | Risk Statements | 25 | | Safety Statements | 46 | | RIDADR | UN 2811 6.1 / PGIII | | WGK Germany | 3 |
| ZM 241385 Usage And Synthesis |
| Biochem/physiol Actions | ZM 241385 is a potent selective adenosine A2A antagonist. The A2A receptor plays a role in regulating myocardial oxygen consumption and coronary blood flow and is highly expressed in the brain, where it has important roles in the regulation of glutamate and dopamine release. ZM 241385 has neuroprotective effects and is being investigated for use in Parkinson′s and other neurodegenerative disorders. |
| ZM 241385 Preparation Products And Raw materials |
| Raw materials | [(2-furanylcarbonyl)amino]--->LUF5443-->5-Furan-2-yl-3-methyl-1H-[1,2,4]triazole-->2-(furan-2-yl)-5-(methylsulfonyl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine-->1H-1,2,4-Triazol-3-amine,5-(2-furanyl)-(9CI)-->Furan-2-carbohydrazide-->2-Furonitrile-->Tyramine |
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