Other grades of this product :
| CGP 52432 Basic information |
| Product Name: | CGP 52432 | | Synonyms: | 3-([[[(3,4-DICHLOROPHENYL)METHYL]AMINO]PROPYL] DIETHOXYMETHYL)PHOSPHINIC ACID;CGP 52432;CGP 52432;CGP-52432;CGP 52432;P52432;Phosphinic acid, P-[3-[[(3,4-dichlorophenyl)methyl]amino]propyl]-P-(diethoxymethyl)-;CGP52432 >=98% (HPLC);(3-((3,4-dichlorobenzyl)amino)propyl)(diethoxymethyl)phosphinic acid | | CAS: | 139667-74-6 | | MF: | C15H24Cl2NO4P | | MW: | 384.24 | | EINECS: | 000-000-0 | | Product Categories: | GABA/Glycine receptor;GABA | | Mol File: | 139667-74-6.mol |
| CGP 52432 Chemical Properties |
| Boiling point | 544.4±50.0 °C(Predicted) | | density | 1.258±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | H2O: soluble1mg/mL, clear (warmed) | | pka | 2.26±0.50(Predicted) | | form | powder | | color | white to beige |
| CGP 52432 Usage And Synthesis |
| Uses | CGP52432 has been used as a γ-aminobutyric acid B (GABAB) antagonist:- to study its effects on the simulation of the onset of status epilepticus (SE) in mice
- for voltage-clamp recording in mice neurons
- to study its effects on the GABAB receptor-mediated neurotransmission in guinea pig hippocampus
| | Biological Activity | Potent, selective GABA B receptor antagonist (IC 50 = 85 nM). | | Biochem/physiol Actions | CGP52432 participates in inhibiting the glycine overflow in the hippocampus. |
| CGP 52432 Preparation Products And Raw materials |
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