7-Diethylamino-3-formyl-4-(4’-methoxyphenyl)coumarin

7-Diethylamino-3-formyl-4-(4’-methoxyphenyl)coumarin
  • CAS No.:1428730-05-5
Other grades of this product :
7-Diethylamino-3-formyl-4-(4’-methoxyphenyl)coumarin Basic information
Product Name:7-Diethylamino-3-formyl-4-(4’-methoxyphenyl)coumarin
Synonyms:7-Diethylamino-3-formyl-4-(4’-methoxyphenyl)coumarin;NeuroSensor 521;7-(Diethylamino)-4-(4-methoxyphenyl)-2-oxo-2H-1-benzopyran-3-carboxaldehyde;NeuroSensor 521 >=98% (HPLC)
CAS:1428730-05-5
MF:C21H21NO4
MW:351.4
EINECS:
Product Categories:
Mol File:1428730-05-5.mol
7-Diethylamino-3-formyl-4-(4’-methoxyphenyl)coumarin Chemical Properties
storage temp. -70°C
solubility DMSO: soluble10mg/mL, clear
form powder
color yellow to orange
Safety Information
Hazard Codes T
Risk Statements 25
Safety Statements 45
RIDADR UN 2811 6.1 / PGIII
WGK Germany 3
MSDS Information
7-Diethylamino-3-formyl-4-(4’-methoxyphenyl)coumarin Usage And Synthesis
UsesNeurosensor 521 is a selective noradrenalin and dopamine fluorescent indicator.
Biochem/physiol ActionsNeuroSensor 521 is a fluorescent turn-on sensor designed for the selective visualization of norepinephrine over epinephrine in fixed and live cells and the fluorescence is not affected by fixation. NeuroSensor 521 binds to all primary amines, but binds catecholamines such as dopamine and norepinephrine more tightly than other biogenic amines such as glutamate and does not interact with secondary amines such as epinephrine. Because of the spectral properties of NeuroSensor 521, the unbound and bound states can be monitored using 440 and 488 nm excitation, respectively. In chromaffin cells NeuroSensor 521 stained the norepinephrine-containing cells preferentially over epinephrine-containing cells under identical conditions.
7-Diethylamino-3-formyl-4-(4’-methoxyphenyl)coumarin Preparation Products And Raw materials

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