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| R-(+)-2-TRIFLUOROMETHYLOXIRANE Basic information |
| Product Name: | R-(+)-2-TRIFLUOROMETHYLOXIRANE | | Synonyms: | R-(+)-2-TRIFLUOROMETHYLOXIRANE, 97;(2R)-2-(trifluoromethyl)oxirane;(2R)-2-(Trifluoromethyl)oxirane (ee);(2R)-(+)-3,3,3-Trifluoro-1,2-propenoxide;(2R)-2-(Trifluoromethyl)oxirane, (2R)-1,2-Epoxy-3,3,3-trifluoropropane;Oxirane, 2-(trifluoromethyl)-, (2R)-;R-(+)-2-TRIFLUOROMETHYLOXIRANE | | CAS: | 143142-90-9 | | MF: | C3H3F3O | | MW: | 112.05 | | EINECS: | | Product Categories: | | Mol File: | 143142-90-9.mol |
| R-(+)-2-TRIFLUOROMETHYLOXIRANE Chemical Properties |
| Boiling point | 25-32 °C | | density | 1.294 g/mL at 25 °C | | refractive index | n20/D <1.300 | | Fp | -15 °F | | storage temp. | 2-8°C |
| Hazard Codes | F+ | | Risk Statements | 12 | | Safety Statements | 3 | | RIDADR | UN 1993 3/PG 1 | | WGK Germany | 3 | | HS Code | 2910900090 |
| R-(+)-2-TRIFLUOROMETHYLOXIRANE Usage And Synthesis |
| Uses | (R)-(+)-3,3,3-Trifluoro-1,2-epoxypropane can be used as a substrate to synthesize: - Substituted trifluoro amino propanols, which are found to be potent inhibitors of cholesteryl ester transfer protein.
- (2R) Trifluoro-(methoxybenzyloxy)-propanol (chiral glycol) by reacting with 4-methoxybenzyl alcohol in the presence of NaH. Chiral glycol intermediate is further utilized for the preparation of trifluoromethyl glycol carbamates as potential monoacylglycerol lipase (MAGL) inhibitors.
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| R-(+)-2-TRIFLUOROMETHYLOXIRANE Preparation Products And Raw materials |
| Raw materials | 3-Bromo-1,1,1-trifluoroacetone-->1,1,1-Trifluoro-2,3-epoxypropane | | Preparation Products | (S)-3,3,3-Trifluoropropane-1,2-diol-->1,1,1-TRIFLUORO-2,3-EPOXYPROPANE |
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