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| OMEGA-AGATOXIN TK Basic information |
| Product Name: | OMEGA-AGATOXIN TK | | Synonyms: | OMEGA-AGA-IVB;OMEGA-AGA-TK;OMEGA-AGATOXIN TK;OMEGA-AGATOXIN TK, AGELENOPSIS APERTA;GLU-ASP-ASN-CYS-ILE-ALA-GLU-ASP-TYR-GLY-LYS-CYS-THR-TRP-GLY-GLY-THR-LYS-CYS-CYS-ARG-GLY-ARG-PRO-CYS-ARG-CYS-SER-MET-ILE-GLY-THR-ASN-CYS-GLU-CYS-THR-PRO-ARG-LEU-ILE-MET-GLU-GLY-LEU-D-SER-PHE-ALA;ω-aga-tk;ω-agatoxin tk;Omega-Agatoxin IVa trifluoroacetate salt H-Lys-Lys-Lys-Cys-Ile-Ala-Lys-Asp-Tyr-Gly-Arg-Cys-Lys-Trp-Gly-Gly-Thr-Pro-Cys-Cys-Arg-Gly-Arg-Gly-Cys-Ile-Cys-Ser-Ile-Met-Gly-Thr-Asn-Cys-Glu-Cys-Lys-Pro-Arg-Leu-Ile-Met-Glu-Gly-Leu-Gly-Leu-Ala-OH trifluoroacetate salt (Disulfide bonds between Cys4 and Cys20/Cys12 and Cys25/Cys19 and Cys36/Cys27 and Cys34) | | CAS: | 145017-83-0 | | MF: | C215H337N65O70S10 | | MW: | 5273.02 | | EINECS: | | Product Categories: | Ion Channels;proteins | | Mol File: | Mol File |
| OMEGA-AGATOXIN TK Chemical Properties |
| storage temp. | -20°C | | solubility | H2O: Aqueous stock solution is stable for 1 month at 2-8°C and for several months at -20°C.soluble | | form | powder |
| OMEGA-AGATOXIN TK Usage And Synthesis |
| Uses | ω-Agatoxin IVA has been used in the manipulation of calcium influx. It has also been used in the study to characterize the spontaneous and evoked activity from murine ventral horn cultures on microelectrode arrays. | | Uses | omega-Agatoxin TK is a selective blocker of the P-type Ca2+?channel. | | General Description | CACNA1A (calcium voltage-gated channel subunit alpha1 A)?gene codes for the α1 subunit of neuronal CaV2.1 (P/Q-type) voltage-gated calcium channels. It is expressed throughout the central nervous system (CNS). CACNA1A gene is located on human chromosome 19p13. | | Biochem/physiol Actions | Toxin found in the venom of the funnel web spider, Agelenopsis aptera. Potent, selective blocker of mammalian P-type voltage-dependent calcium channels. |
| OMEGA-AGATOXIN TK Preparation Products And Raw materials |
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