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| ADRENOMEDULLIN (HUMAN) Basic information |
| Product Name: | ADRENOMEDULLIN (HUMAN) | | Synonyms: | H-TYR-ARG-GLN-SER-MET-ASN-ASN-PHE-GLN-GLY-LEU-ARG-SER-PHE-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-VAL-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-ASN-VAL-ALA-PRO-ARG-SER-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2;H-TYR-ARG-GLN-SER-MET-ASN-ASN-PHE-GLN-GLY-LEU-ARG-SER-PHE-GLY-CYS-ARG-PHE-GLY-THR-CYS-THR-VAL-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-ASN-VAL-ALA-PRO-ARG-SER-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2 (DISULFIDE BRIDGE: 16-21);ADM 1-52, HUMAN;ADRENOMEDULLIN (HUMAN);ADRENOMEDULLIN 1-52, HUMAN;humanadrenomedullin;adrenomedullin 52 human;YRQSMNNFQGLRSFGCRFGTCTVQKLAHQIYQFTDKDKDNVAPRSKISPQGY-NH2 (DISULFIDE BRIDGE: 16-21) | | CAS: | 148498-78-6 | | MF: | C264H406N80O77S3 | | MW: | 6028.73324 | | EINECS: | | Product Categories: | proteins;AdrenomedullinPeptides for Cell Biology;Adrenomedullins;Hormones;Miscellaneous Peptides;Other Protein/Peptide Hormones;Peptide | | Mol File: | 148498-78-6.mol |
| ADRENOMEDULLIN (HUMAN) Chemical Properties |
| storage temp. | -20°C | | solubility | Soluble at 1mg/ml in 1% acetic acid | | form | powder |
| WGK Germany | 3 | | RTECS | AV6800000 | | HS Code | 2937190000 |
| ADRENOMEDULLIN (HUMAN) Usage And Synthesis |
| Uses | Peptide elicits potent hypotensive effect, comparable to calcitonin gene-related peptide. Plays a key role in regulating endometrial angiogenesis. | | General Description | Adrenomedullin (ADM) human comprises of 52 amino acids and has amine group in the C-terminal tyrosine residue. It also has a N-terminal ring structure and belongs to calcitonin peptide family. ADM has vasodilatory function and is mapped to human chromosome 11p15.4. Adrenomedullin is highly expressed in endothelial cells. Adrenomedullin controls a majority of cellular processes using cyclic adenosine monophosphate (cAMP) as a messenger. It interacts with calcitonin receptor-like receptor (CRLR) and receptor activity modifying protein 2 (RAMP2). ADM contributes to invasion activity in brain tumor cell lines. ADM signalling plays a key role in tumor progression, especially in acute myeloid leukemia. | | Biochem/physiol Actions | Peptide elicits potent hypotensive effect, comparable to calcitonin gene-related peptide. Plays a key role in regulating endometrial angiogenesis. |
| ADRENOMEDULLIN (HUMAN) Preparation Products And Raw materials |
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