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| ZINQUIN ETHYL ESTER Basic information |
| Product Name: | ZINQUIN ETHYL ESTER | | Synonyms: | ETHYL [2-METHYL-8-[[(4-METHYLPHENYL)SULFONYL]AMINO]-6-QUINOLINYL]OXY ACETATE;ETHYL(2-METHYL-8-P-TOLUENESULFONAMIDO-6-QUINOLYLOXY)ACETATE;ZINQUIN-E;ZINQUIN ETHYL ESTER;2-METHYL-8-[(4-METHYLPHENYL)SULFONYLAMINO]-6-(ETHYLOXYCARBONYLMETHYLOXY)QUINOLINE;2-METHYL-8-(4-METHYLPHENYLSULFONYLAMINO)QUINOLINYL]OXYACETIC ACID ETHYL ESTER;Ethyl[[2-mthyl-8-[[(4methylphenyl)sulfonyl]amino]-6-quinolinyl]oxy]acetate;ETHYL[[2-METHYL-8-[[(4-METHYLPHENYL)SULFONYL]AMINO]-6-QUINOLINYL]OXY]ACETATE (ZINQUIN ETHYL ESTER) | | CAS: | 151606-29-0 | | MF: | C19H18N2O5S | | MW: | 386.42 | | EINECS: | | Product Categories: | Quinoline;Chelating Agents, Ligands;Chelating Agents & Ligands;Fluorescent Labels & Indicators | | Mol File: | 151606-29-0.mol |
| ZINQUIN ETHYL ESTER Chemical Properties |
| Melting point | 112-114°C | | Boiling point | 608.0±65.0 °C(Predicted) | | density | 1.412±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: soluble | | form | crystals | | pka | pK1 (quinoline nitrogen): <2; pK (carboxylic acid proton): 5.77 ±0.03; pK (sulfonamide proton): 9.91±0.02(at 25℃) | | color | off-white | | λmax | 368 nm | | Biological Applications | Zinc indicator; detecting apoptosis |
| ZINQUIN ETHYL ESTER Usage And Synthesis |
| Chemical Properties | White or Pale Blue Crystalline Solid | | Uses | A fluorescent reagent and indicator of intracellular zinc ions. An analogue of widely used indicator, TS-Q. Zinquin ethyl ester is membrane permeable therefore useful to detect intracellular zinc ions. Zinquin ethyl ester forms a complex with a zin | | Uses | Zinquin ethyl ester is a lipophilic, zinc-sensitive, cell-permeable fluorescnet probe. | | Biochem/physiol Actions | Zinquin is a membrane-permeant fluorophore. It is used to detect zinc in cells by UV fluorescence. Zinquin ethyl ester can be used to monitor the change in intracellular concentrations of Zn2+ in thymocytes and hepatocytes. The ester is excited at 368nm and emits at 490nm. |
| ZINQUIN ETHYL ESTER Preparation Products And Raw materials |
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