Seractide

Seractide
  • CAS No.:12279-41-3
Other grades of this product :
Seractide Basic information
Product Name:Seractide
Synonyms:CORTICOTROPIN (HUMAN);CORTICOTROPHIN;CORTICOTROPIN A;H-SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-GLY-LYS-LYS-ARG-ARG-PRO-VAL-LYS-VAL-TYR-PRO-ASN-GLY-ALA-GLU-ASP-GLU-SER-ALA-GLU-ALA-PHE-PRO-LEU-GLU-PHE-OH;ACTH (1-39) (huMan) Corticotropin;Adrenocorticotropic Hormone (ACTH) (1-39);Seractide acetate;Adrenocorticotropic Hormone (ACTH) (1-39), human
CAS:12279-41-3
MF:C207H308N56O58S1
MW:4541.07
EINECS:634-154-0
Product Categories:Peptide;Melanocortin receptor
Mol File:12279-41-3.mol
Seractide Chemical Properties
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility H2O: 1 mg/mL, clear, colorless
form Solid
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-40
Safety Statements 22-36
WGK Germany 3
RTECS GM7900000
8-10
MSDS Information
ProviderLanguage
SigmaAldrich English
Seractide Usage And Synthesis
UsesHormone (adrenocorticotropic).
Brand nameActhar Gel-Synthetic (Armour).
General DescriptionAdrenocorticotropic hormone (ACTH) is a 303-amino acid hormone protein, which is located at human chromosome 2p23.3.
Biochem/physiol ActionsAdrenocorticotropic hormone (ACTH) stimulates melanocortin receptor (MC1R to MC5R).It is implicated in the production of α-melanocyte-stimulating hormone (α-MSH). Hypomethylation of ACTH promoter region in thymic carcinoids is associated with ectopic adrenocorticotropic hormone syndrome. Mutations in this gene are associated with aberrant fusion protein and impairing melanocortin signaling in hypoadrenalism. Dysregulation of ACTH leads to Cushing disease.
Seractide Preparation Products And Raw materials

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