Other grades of this product :
| IB-MECA Basic information |
| Product Name: | IB-MECA | | Synonyms: | PICLIDENOSON;CF-101;(2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(3-iodobenzylamino)-9H-purin-9-yl)-N-methyltetrahydrofuran-2-carboxamide;CS-2564;IBMECA;(PICLIDENOSON; CF-101;1-DEOXY-1-[6-[[(3-IODOPHENYL)METHYL]AMINO]-9H-PURIN-9-YL]-N-METHYL-BETA-D-RIBOFURANURON-AMIDE;Selepressin;RPR-113090;3-iodobenzyl-5'-N-methylcarboxamidoadenosine | | CAS: | 152918-18-8 | | MF: | C18H19IN6O4 | | MW: | 510.29 | | EINECS: | | Product Categories: | | Mol File: | 152918-18-8.mol |
| IB-MECA Chemical Properties |
| density | 1.98±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | hot ethanol: >10 mg/mL | | pka | 12.72±0.70(Predicted) | | form | solid | | color | white | | InChIKey | HUJXGQILHAUCCV-MOROJQBDSA-N |
| IB-MECA Usage And Synthesis |
| Uses | IB-MECA has been used for intraocular pressure and corneal thickness measurements in rabbits. | | Definition | ChEBI: A derivative of adenosine in which the 5'-hydroxymethyl group is replaced by N-ethylcarboxamido and one of the hydrogens of the exocyclic amino function is substituted by a 3-iodobenzyl group. | | Biological Activity | Potent and selective A 3 adenosine receptor agonist (K i values are 1.1, 54 and 56 nM for A 3 , A 1 and A 2A receptors respectively). Cardioprotective, reduces infarct size upon reperfusion in rats. | | Biochem/physiol Actions | Selective A3 adenosine receptor agonist. |
| IB-MECA Preparation Products And Raw materials |
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