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| Lanicemine dihydrochloride Basic information |
| Product Name: | Lanicemine dihydrochloride | | Synonyms: | AR-R 15896 dihydrochloride;AZD6765 dihydrochloride;FPL 15896 dihydrochloride;Lanicemine dihydrochloride;ARL-15896;AZD6765;(αS)-α-Phenyl-2-pyridineethanamine dihydrochloride;ARL15896; ARL 15896; LANICEMINE HYDROCHLORIDE; AR-R15896AR | | CAS: | 153322-06-6 | | MF: | C13H15ClN2 | | MW: | 234.73 | | EINECS: | | Product Categories: | | Mol File: | 153322-06-6.mol |
| Lanicemine dihydrochloride Chemical Properties |
| storage temp. | 2-8°C | | solubility | H2O: soluble20mg/mL, clear | | form | powder | | color | white to beige |
| Hazard Codes | T | | Risk Statements | 25 | | Safety Statements | 45 | | RIDADR | UN 2811 6.1 / PGIII | | WGK Germany | 3 |
| Lanicemine dihydrochloride Usage And Synthesis |
| Uses | AZD6765 dihydrochloride has been used as an antidepressant?to improve behavior and metabolic measures?in chronic unpredictable mild stress (CUMS). | | Biochem/physiol Actions | AZD6765 is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist and fast-acting antidepressant. In a recent study AZD6765 relieved depression within 80 minutes, unlike most antidepressants acting on serotonin or dopamine systems which can take several weeks to work. The effects lasted from about an hour up to 2 weeks. AZD6765 has an IC50 value of 1.3 μM. Unlike more potent drugs such as ketamine, which also has rapid antidepressant activity, AZD6765 has no dissociative side-effects such as hallucinations. Earlier studies inidcated the compound has neuroprotective and anticonvulsant effects. |
| Lanicemine dihydrochloride Preparation Products And Raw materials |
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