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| Ertapenem sodium Basic information |
| Product Name: | Ertapenem sodium | | Synonyms: | 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-(((3S,5S)-5-(((3-ca rboxyphenyl)amino)carbonyl)-3-pyrrolidinyl)thio)-6-((1R)-1-hydroxyethy l)-4-methyl-7-oxo-, monosodium salt, (4R,5S,6S)-;(4R,5S,6S)-3-[[(3S,5S)-5-[[(3-Carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid sodium salt (1:1);ErtapeneM MonosodiuM;Invanz;L 749345;EtapeneM,Invanz,MK-0826,L-749,345;EtapeneM;ErtapeneM Crude | | CAS: | 153773-82-1 | | MF: | C22H26N3NaO7S | | MW: | 499.51 | | EINECS: | 1308068-626-2 | | Product Categories: | | Mol File: | 153773-82-1.mol |
| Ertapenem sodium Chemical Properties |
| Melting point | >174oC (dec.) | | storage temp. | -70°C | | solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated) | | form | powder | | color | white to beige | | Water Solubility | Fully miscible in water. Soluble in DMSO. | | Stability: | Hygroscopic, Temperature Sensitive |
| Ertapenem sodium Usage And Synthesis |
| Uses | Ertapenem sodium has been used as a carbapenem in the NitroSpeed-Carba NP test in minimum inhibitory concentration (MIC) testing for differentiation of carbapenemases in Enterobacterales and Pseudomonas aeruginosa. It has also been used as an antibiotic to study its effects on the survival of septic mice. | | Definition | ChEBI: The monosodium salt of ertapenem. It is used for the treatment of moderate to severe susceptible infections including intra-abdominal and acute gynaecological infections, pneumonia, and infections of the skin and of the urinary tract. It is more stable to
renal dehydropeptidase I tham imipenem, and so unlike imipenem, its use with cilastatin, which inhibits the enzyme, is not required. | | Biochem/physiol Actions | Ertapenem is a broad spectrum carbopenem antibiotic. Ertapenem is active against both gram-positive and gram-negative bacteria. Ertapenem shows an extended duration of action in vivo due to its reversible binding to serum protein. |
| Ertapenem sodium Preparation Products And Raw materials |
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