Other grades of this product :
| PF-04965842(Abrocitinib) Basic information |
| Product Name: | PF-04965842(Abrocitinib) | | Synonyms: | PF-04965842;Abrocitinib;rel-N-((1s,3s)-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutyl)propane-1-sulfonamide;PF-04965842;PF 04965842;PF04965842;N-[cis-3-(Methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclobutyl]-1-propanesulfonamide;PF-04965842;ABROCITINIB;ABROCITINIB (PF-04965842);PF-04965842; PF 04965842; PF04965842; ABROCITINIB | | CAS: | 1622902-68-4 | | MF: | C14H21N5O2S | | MW: | 323.41 | | EINECS: | | Product Categories: | APIS;api | | Mol File: | 1622902-68-4.mol |
| PF-04965842(Abrocitinib) Chemical Properties |
| density | 1.36±0.1 g/cm3(Predicted) | | storage temp. | room temp | | form | powder | | pka | 10.55±0.40(Predicted) | | color | white to beige |
| PF-04965842(Abrocitinib) Usage And Synthesis |
| Biochem/physiol Actions | PF-04965842 is a Janus Kinase (JAK) inhibitor selective for JAK1 with an IC50 value of 29 nM for JAK1 compared to 803 nM for JAK2, >10000 nM for JAK3 and 1250 nM for Tyk2. JAKs mediate cytokine signaling, and are involved in cell proliferation and differentiation. PF-04965842 has been investigated as a possible treatment for psoriasis. |
| PF-04965842(Abrocitinib) Preparation Products And Raw materials |
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