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| (S)-3,5-DIHYDROXYPHENYLGLYCINE Basic information |
| Product Name: | (S)-3,5-DIHYDROXYPHENYLGLYCINE | | Synonyms: | (S)-3,5-DIHYDROXYPHENYLGLYCINE;(S)-3,5-DHPG;S-DHPG;(S)-3,5-Dihydroxyphenylglycine hydrate;+-2,5-DIMETHOXY-4-IODOAMPHETAMINE HYDROCHLORIDE;(S)-3,5-Dihydroxylphenylglycine;Benzeneacetic acid, α-amino-3,5-dihydroxy-, (αS)-;(2S)-2-amino-2-(3,5-dihydroxyphenyl)acetic acid | | CAS: | 162870-29-3 | | MF: | C8H9NO4 | | MW: | 183.16 | | EINECS: | 2017-001-1 | | Product Categories: | Glutamate receptor;Glutamate | | Mol File: | 162870-29-3.mol |
| (S)-3,5-DIHYDROXYPHENYLGLYCINE Chemical Properties |
| Melting point | >207°C (dec.) | | Boiling point | 448.8±33.0 °C(Predicted) | | density | 1.550±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | Aqueous Base (Very Slightly, Sonicated), Methanol (Slightly), Water (Slightly, H | | form | solid | | pka | 1.77±0.10(Predicted) | | color | white | | Stability: | Hygroscopic |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 |
| (S)-3,5-DIHYDROXYPHENYLGLYCINE Usage And Synthesis |
| Uses | (S)-3,5-Dihydroxylphenylglycine is a potent agonist of group I metabotropic glutamate receptors mGluR1 and mGluR5. (S)-3,5-Dihydroxylphenylglycine have been utilized for the treatment of neuronal inju
ry and cognitive enhancement. | | Uses | (S)-3,5-Dihydroxylphenylglycine is a potent agonist of group I metabotropic glutamate receptors mGluR1 and mGluR5. (S)-3,5-Dihydroxylphenylglycine have been utilized for the treatment of neuronal injury and cognitive enhancement. | | Uses | (S)-3,5-Dihydroxyphenylglycine hydrate has been used: - as mGluR1/5?agonist for metabotropic glutamate receptor 1 (mGluR1/5) activation in synaptoneurosomal preparations
- in ACSF for DHPG stimulation
- to inject into basolateral amygdala to study its effect on memory expression
| | Biological Activity | Selective group I mGlu receptor agonist. Also available as part of the Group I mGlu Receptor Tocriset™ and Mixed mGlu Receptor Tocriset™ . | | Biochem/physiol Actions | (S)-3,5-Dihydroxyphenylglycine hydrate is a group I metabotropic glutamate receptor agonist. |
| (S)-3,5-DIHYDROXYPHENYLGLYCINE Preparation Products And Raw materials |
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