Other grades of this product :
| Lu 28-179 Basic information |
| Product Name: | Lu 28-179 | | Synonyms: | Siramesine fumarate salt;Siramesine (fumarate);Lu 28-179;1′-[4-[1-(4-Fluorophenyl)indol-3-yl]butyl]spiro[1H-2-benzofuran-3,4′-piperidine] fumarate salt;Siramesine fumarate salt >=98% (HPLC) | | CAS: | 163630-79-3 | | MF: | C34H35FN2O5 | | MW: | 570.6505032 | | EINECS: | | Product Categories: | | Mol File: | 163630-79-3.mol |
| Lu 28-179 Chemical Properties |
| storage temp. | 2-8°C | | solubility | DMSO: soluble20mg/mL, clear | | form | powder | | color | white to beige |
| Lu 28-179 Usage And Synthesis |
| Biochem/physiol Actions | Siramesine is a blood-brain barrier penetrant, selective and potent sigma-2 receptor agonist, which exhibits potent and very long-lasting anxiolytic effects in rodents. Also, siramesine is a lysosome-destabilizing agent that causes lysosomal cell death in varies immortalized and cancer cell lines. |
| Lu 28-179 Preparation Products And Raw materials |
|