METHOXYVERAPAMIL HYDROCHLORIDE

CAS No.：16662-47-8

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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METHOXYVERAPAMIL HYDROCHLORIDE Basic information

Product Name:	METHOXYVERAPAMIL HYDROCHLORIDE
Synonyms:	5-[(3,4-Dimethoxyphenethyl)methylamino]-2-isopropyl-2-(3,4,5-trimethoxyphenyl)valeronitrile;5-[[2-(3,4-Dimethoxyphenyl)ethyl](methyl)amino]-2-isopropyl-2-(3,4,5-trimethoxyphenyl)pentanenitrile;Methoxyverapamil;C13764;5-((3,4-diMethoxyphenethyl)(Methyl)aMino)-2-isopropyl-2-(3,4,5-triMethoxyphenyl)pentanenitrile;5-((3,4-diMethoxyphenethyl)(Methyl)aMino)-2-isopropyl-2-(3,4,5-triMethoxyphenyl)pentanenitrile HCl;CoMpound D 600;D 600 (vasodilator)
CAS:	16662-47-8
MF:	C28H40N2O5
MW:	484.63
EINECS:
Product Categories:
Mol File:	16662-47-8.mol

METHOXYVERAPAMIL HYDROCHLORIDE Chemical Properties

Boiling point	605.9±55.0 °C(Predicted)
density	1.068±0.06 g/cm3(Predicted)
refractive index	nD25 1.5402
form	White to off-white solid.
pka	8.96±0.50(Predicted)

Safety Information

WGK Germany

MSDS Information

METHOXYVERAPAMIL HYDROCHLORIDE Usage And Synthesis

Uses	(±)-Methoxyverapamil hydrochloride has been used: as calcium channel antagonist in Schistosoma mansoni parasite as calcium entry blocker in cultured macrophages in the inhibition of L-type voltage gated Ca₂⁺-channels
General Description	Methoxyverapamil is a calmodulin antagonist. It controls flagellar glycoprotein redistribution by modulating calcium signalling. Methoxyverapamil impacts the effect of intracellular calcium levels and affects the sperm capacitation function.
Biochem/physiol Actions	Blocks L-type Ca2+ channels

METHOXYVERAPAMIL HYDROCHLORIDE Preparation Products And Raw materials

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