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| 4-HYDROXYANTIPYRINE Basic information |
| Product Name: | 4-HYDROXYANTIPYRINE | | Synonyms: | 4-HYDROXYANTIPYRINE;4-HYDROXY-2,3-DIMETHYL-1-PHENYL-3-PYRAZOLIN-5-ONE;1,5-Dimethyl-2-phenyl-4-hydroxy-4-pyrazoline-3-one;2,3-Dihydro-4-hydroxy-1,5-dimethyl-2-phenyl-1H-pyrazol-3-one;4-hydroxy-1,5-dimethyl-2-phenyl-pyrazol-3-one;4-hydroxy-1,5-dimethyl-2-phenylpyrazol-3-one;NSC 174055;4-Hydroxy-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one | | CAS: | 1672-63-5 | | MF: | C11H12N2O2 | | MW: | 204.23 | | EINECS: | | Product Categories: | Heterocyclic Compounds | | Mol File: | 1672-63-5.mol |
| 4-HYDROXYANTIPYRINE Chemical Properties |
| Melting point | 184-186 °C (lit.) | | Boiling point | 314.3±52.0 °C(Predicted) | | density | 1.294±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 11.99±0.20(Predicted) | | form | neat | | color | Off-White to Beige |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 |
| 4-HYDROXYANTIPYRINE Usage And Synthesis |
| Uses | Antipyrine metabolite | | Uses | 4-Hydroxyantipyrine is a metabolite of antipyrine (A697500) which is an analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. | | Uses | 4-Hydroxyantipyrine was used to study the relationships between the metabolism of antipyrine, hexobarbitone and theophylline in man. It was used in a study on flow injection analysis system for the characterisation of pharmaceutical compounds via combination of diode array UV, 1H NMR, FT-IR spectroscopy and time-of-flight mass spectrometry. | | General Description | 4-Hydroxyantipyrine is formed during oxidative deamination of aminopyrine. It is a metabolite of antipyrine. |
| 4-HYDROXYANTIPYRINE Preparation Products And Raw materials |
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