ADENOSINE 2' -& 3'-MONOPHOSPHATE FREE

CAS No.：130-49-4

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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ADENOSINE 2' -& 3'-MONOPHOSPHATE FREE Basic information

Product Name:	ADENOSINE 2' -& 3'-MONOPHOSPHATE FREE
Synonyms:	-MONOPHOSPHATE FREE;adenosine2’-phosphoricacid;Adenosine 2'(3')-Monophosphate(2',3'mixed);2'-, and 3'-adenylic acid, mixed isomers;Ado-2'-P;Adenylic Acid Hydrate;Adenosine-2'(3')-monophosphoric acid (mixed isomers);adenosine 2'-phosphate hemihydrate
CAS:	130-49-4
MF:	C10H14N5O7P
MW:	347.22
EINECS:	204-990-7
Product Categories:	Biochemistry;Nucleosides, Nucleotides & Related Reagents;Nucleotides and their analogs
Mol File:	130-49-4.mol

ADENOSINE 2' -& 3'-MONOPHOSPHATE FREE Chemical Properties

Melting point	183 °C
Boiling point	815.5±75.0 °C(Predicted)
density	2.3200 (rough estimate)
refractive index	1.9050 (estimate)
storage temp.	-20°C
pka	pK1: 3.81(+1);pK2: 6.17(0) (25°C)
Water Solubility	0.5g/L(15 ºC)
Merck	157

Safety Information

WGK Germany	3
RTECS	AU7480300

MSDS Information

ADENOSINE 2' -& 3'-MONOPHOSPHATE FREE Usage And Synthesis

Chemical Properties

colorless or white to yellowish powder

Uses

Adenosine 2′-monophosphate (2′-AMP) is a metabolite produced from hydrolysis of 2′,3′-cAMP. 2′-AMP inhibits proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. 2′-AMP is used in the synthesis of a new photoaffinity lable for the coenzyme site of porcine NADP-specific isocitrate dehydrogenase. 2′,3′-cAMP and 2′-AMP represent a new unexplored pathway for adenosine-based cell regulation.

ADENOSINE 2' -& 3'-MONOPHOSPHATE FREE Preparation Products And Raw materials

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