1,3-Bis(4-piperidyl)propane

CAS No.：16898-52-5

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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1,3-Bis(4-piperidyl)propane Basic information

Product Name:	1,3-Bis(4-piperidyl)propane
Synonyms:	1,3-BIS(4-PIPERIDYL)PROPANE 97%;1,3-DI-4-PIPERIDYLPROPANE 98%;4,4-TRIMETHYLENEDIPIPERIDINE 98%;1,3-Bis(4-piperidino)propane, 97+%;1,3-Bis(4-piperidyl)propane, tech., 95%;1,3-Bis(4-piperidino)propane;1,3-Di(4-piperidinyl)propane;4,4'-(1,3-Propanediyl)dipiperidine
CAS:	16898-52-5
MF:	C13H26N2
MW:	210.36
EINECS:	240-941-6
Product Categories:	API intermediates;Building Blocks;Heterocyclic Building Blocks;Piperidines
Mol File:	16898-52-5.mol

1,3-Bis(4-piperidyl)propane Chemical Properties

Melting point	65-68.5 °C(lit.)
Boiling point	327°C
density	0.9578 (rough estimate)
vapor pressure	0.022Pa at 25℃
refractive index	1.5032 (estimate)
Fp	327°C
pka	10.99±0.10(Predicted)
form	powder to crystal
color	White to Light yellow
Water Solubility	almost transparency
Sensitive	Hygroscopic
BRN	111615
LogP	3.36 at 20℃
CAS DataBase Reference	16898-52-5(CAS DataBase Reference)
NIST Chemistry Reference	Piperidine, 4,4'-(1,3-propanediyl)bis-(16898-52-5)
EPA Substance Registry System	Piperidine, 4,4'-(1,3-propanediyl)bis- (16898-52-5)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-37/39
WGK Germany	3
TSCA	Yes
HazardClass	IRRITANT
HS Code	2933399990

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

1,3-Bis(4-piperidyl)propane Usage And Synthesis

Uses	4,4′-Trimethylenedipiperidine was used in the synthesis of hyperbranched copolymers from commercially available monomers: divinylsulfone, 4,4′-trimethylenedipiperidine and N-ethylenediamine. It was used in the synthesis of two- and three-dimensional cadmium-organic frameworks.
General Description	4,4′-Trimethylenedipyridine undergoes Willgerodt-Kindler reaction by on pot- polycondensation with dialdehydes in the presence of sulphur to form polythioamides.
Flammability and Explosibility	Notclassified

1,3-Bis(4-piperidyl)propane Preparation Products And Raw materials

Preparation Products

4,4'-Trimethylenedipyridine

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