Other grades of this product :
| CASPASE-3 Basic information |
| Product Name: | CASPASE-3 | | Synonyms: | PROCASPASE-3;PROCASPASE-3, HIS TAG(R) HUMAN;PROCASPASE-3, HIS TAG(R), MOUSE;PROCASPASE-3 (HUMAN);PRO-CASPASE-3 (HUMAN) (REC);PRO-CASPASE-3 (HUMAN) (RECOMBINANT);PROCASPASE-3, HUMAN, RECOMBINANT, E COLI;YAMA | | CAS: | 169592-56-7 | | MF: | | MW: | 0 | | EINECS: | | Product Categories: | | Mol File: | Mol File |
| CASPASE-3 Chemical Properties |
| Melting point | 127 °C | | storage temp. | −70°C | | solubility | PBS: soluble | | form | buffered aqueous glycerol solution |
| CASPASE-3 Usage And Synthesis |
| Uses | Caspase 3 human has been used to digest human r-vimentin. It has also been used in caspase-3 inhibition assay and protease inhibition assay. | | General Description | Human recombinant C-terminal histidine tagged caspase 3 is a fully active protein consisting of 17 kDa and 13.5 kDa subunits; the 13.5 kDa subunit contains the histidine tag. | | Biochem/physiol Actions | Caspase 3 is a member of the CED-3 subfamily of caspases and is responsible for the cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP), the inhibitor of caspase-activated deoxyribonuclease (ICAD), and gelsolin, a protein involved in apoptosis regulation. Caspase?3 is considered to be an effector caspase, activating pro-caspase?6 and pro-caspase?9 in vitro. Caspase 3 can be activated by caspase 8, caspase 6, and granzyme B. |
| CASPASE-3 Preparation Products And Raw materials |
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