Other grades of this product :
| FTI-276 Basic information |
| Product Name: | FTI-276 | | Synonyms: | N-[4-[2-(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE TRIFLUOROACETATE SALT;N-[2-PHENYL-4-N[2(R)-AMINO-3-MERCAPTOPROPYLAMINO BENZOYL]-METHIONINE, TFA;FTI-276;FTI-276 trifluoroacetate salt;ZIXDDEATQSBHHL-BEFAXECRSA-N;L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]- | | CAS: | 170006-72-1 | | MF: | C21H27N3O3S2 | | MW: | 433.59 | | EINECS: | | Product Categories: | | Mol File: | Mol File |
| FTI-276 Chemical Properties |
| Boiling point | 715.6±60.0 °C(Predicted) | | density | 1.272±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | H2O: >5 mg/mL, soluble | | pka | 3.54±0.10(Predicted) | | form | solid | | color | off-white |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 |
| FTI-276 Usage And Synthesis |
| Uses | N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine Trifluoroacetate Salt is a useful intermediate. | | Biochem/physiol Actions | FTI-276 is a highly potent RasCAAX peptidomimetic. FTI-276 antagonizes both H and K-Ras oncogenic signaling. It is an inhibitor of farnesyltransferase (Ftase) in vitro with an IC50 of 500 pM and is an anti-cancer agent. |
| FTI-276 Preparation Products And Raw materials |
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