Protopine

Protopine
  • CAS No.:130-86-9
Other grades of this product :
Protopine Basic information
Product Name:Protopine
Synonyms:7,13a-Secoberbin-13a-one, 7-methyl-2,3:9,10-bis(methylenedioxy)-;7-Methyl-6,8,9,16-tetrahydrodi[1,3]benzodioxolo[4,5-c:5,6-g]azecin-15(7H)-one;Biflorine;Bis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-;Corydinine;Hypercorine;Protopin;BIFLORIN
CAS:130-86-9
MF:C20H19NO5
MW:353.37
EINECS:204-999-6
Product Categories:chemical reagent;pharmaceutical intermediate;Aromatics;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:130-86-9.mol
Protopine Chemical Properties
Melting point 203-205?C
Boiling point 486.8°C (rough estimate)
density 1.399 (calc)
refractive index 1.5800 (estimate)
storage temp. Inert atmosphere,2-8°C
Water Solubility Insoluble in water
form powder to crystal
color White to Light gray to Light yellow
NIST Chemistry ReferenceProtopine(130-86-9)
Safety Information
Safety Statements 24/25
RIDADR 1544
RTECS VS2800000
HazardClass 6.1(b)
PackingGroup III
HS Code 29391900
Hazardous Substances Data130-86-9(Hazardous Substances Data)
Protopine Usage And Synthesis
Chemical PropertiesOff-White Solid
UsesProtopine is a Ca2+ channel blocker and antiplatelet agent. Immunomodulator
DefinitionChEBI: A dibenzazecine alkaloid isolated from Fumaria vaillantii.
General DescriptionThis substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Purification MethodsIt crystallises from EtOH/CHCl3. The picrate has m ~240o(dec). [Beilstein 27 H 558, 17 I 568, 17 II 620, 17 III/IV 6881.]
Protopine Preparation Products And Raw materials

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