LEPTIN, MOUSE

LEPTIN, MOUSE
  • CAS No.:181030-10-4
Other grades of this product :
LEPTIN, MOUSE Basic information
Product Name:LEPTIN, MOUSE
Synonyms:BETA-RMOB;MURINE OB;MURINE OBESITY PROTEIN;MURINE LEPTIN;MOUSE LEPTIN;MOUSE OB;OB MOUSE;OB GENE PRODUCT (MOUSE)
CAS:181030-10-4
MF:
MW:0
EINECS:
Product Categories:
Mol File:Mol File
LEPTIN, MOUSE Chemical Properties
storage temp. −20°C
form lyophilized powder
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
LEPTIN, MOUSE Usage And Synthesis
UsesLeptin from mouse has been used:
  • to check the effect of leptin on ovulation for treating infertility in obese mice
  • to check the effect of leptin on MGARP (mitochondria-localized glutamic acid-rich protein) expression in testis and follicular granular cells of mice
  • to study the morphometrical changes in mouse testicular tissue upon long term exposure to leptin
Biochem/physiol ActionsLeptin is a hormone produced primarily in adipocytes, although leptin mRNA has also been identified in placenta and fetal tissues, gastric tissue and liver. Its primary site of action appears to be on neurons in the hypothalamus that are involved in regulating energy balance, appetite, and body weight. Leptin increases the production of nitric oxide in endothelial cells and stimulates angiogenesis in vitro and in vivo.Human and mouse leptin share ~84% sequence identity.
LEPTIN, MOUSE Preparation Products And Raw materials

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