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| NETROPSIN DIHYDROCHLORIDE HYDRATE Basic information |
| Product Name: | NETROPSIN DIHYDROCHLORIDE HYDRATE | | Synonyms: | 1H-Pyrrole-2-carboxamide, 4-(aminoiminomethyl)aminoacetylamino-N-5-(3-amino-3-iminopropyl)aminocarbonyl-1-methyl-1H-pyrrol-3-yl-1-methyl-, dihydrochloride;Netropsin hydrate dihydrochloride;Nsc275885;Netropsin, 2 HCl, Streptomycesnetropsis (1.24791);NETROPSIN DIHYDROCHLORIDE HYDRATE 96%;netropsin2HClhydrate | | CAS: | 18133-22-7 | | MF: | C18H27ClN10O3 | | MW: | 466.93 | | EINECS: | | Product Categories: | | Mol File: | 18133-22-7.mol |
| NETROPSIN DIHYDROCHLORIDE HYDRATE Chemical Properties |
| storage temp. | 2-8°C | | solubility | H2O: soluble1mg/mL | | form | powder | | color | faint yellow |
| Hazard Codes | Xn | | Risk Statements | 20/21/22 | | Safety Statements | 36/37 | | RIDADR | UN 2811 6.1 / PGIII | | WGK Germany | 3 | | RTECS | DW2973000 | | HS Code | 2941900000 |
| NETROPSIN DIHYDROCHLORIDE HYDRATE Usage And Synthesis |
| Uses | Netropsin Dihydrochloride is DNA minor groove binding ligand. | | Biochem/physiol Actions | Netropsin is an unusual n-methylpyrrole-containing oligopeptide that binds to AT-rich sequences of dsDNA, especially in the minor groove. Thus, it protects such regions from DNase I and other endonucleases, and also inhibits topoisomerases. Netropsin disrupts the cell cycle, prolonging G and arresting in G. |
| NETROPSIN DIHYDROCHLORIDE HYDRATE Preparation Products And Raw materials |
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