Azidoacetic acid methyl ester

CAS No.：1816-92-8

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

View the full Disclaimer

Other grades of this product :

Azidoacetic acid methyl ester Basic information

Product Name:	Azidoacetic acid methyl ester
Synonyms:	Azidoacetic acid methyl ester;2-Azido-acetic acid Methyl ester;Acetic acid, 2-azido-, Methyl ester;Methyl 2-azidoacetate 97%;Methyl 2-azidoacetate - M3461
CAS:	1816-92-8
MF:	C3H5N3O2
MW:	115.0907
EINECS:
Product Categories:
Mol File:	1816-92-8.mol

Azidoacetic acid methyl ester Chemical Properties

Boiling point	35 °C
density	1.182 g/mL at 25 °C
refractive index	n20/D1.440
Fp	48℃

Safety Information

Hazard Codes	Xi
Risk Statements	5-10-36/37/38
Safety Statements	26
RIDADR	UN 1993C 3 / PGIII
WGK Germany	3

MSDS Information

Azidoacetic acid methyl ester Usage And Synthesis

Uses

Methyl 2-azidoacetate is widely used as a precursor to build triazole derivatives via alkyne-azide click chemistry. Some of the examples include the synthesis of coumarin-triazole derivatives as potential antiplasmodial agents and macrocyclic triazole containing largazole analogs as histone deacetylases-1 (HDAC1) inhibitors.
It can be used to synthesize various pyrrole derivatives by Knoevenagel condensation as in the synthesis of near-infrared boron dipyrromethene (BODIPY) donors for organic tandem solar cells.
It can also be used in Hemetsberger-Knittel synthesis of substituted 5-, 6-, and 7-azaindoles.
Synthesis of highly fluorescent pyreno[2,1-b]pyrroles using methyl 2-azidoacetate as one of the reagents.

Azidoacetic acid methyl ester Preparation Products And Raw materials

Raw materials	Tetrabutylammonium azide-->Methyl chloroacetate-->Glycine methyl ester hydrochloride-->Methyl bromoacetate
Preparation Products	1H-Indole, 6-chloro-7-fluoro--->METHYL N-ACETYLGLYCINATE-->N-(DIPHENYLMETHYLENE)GLYCINE METHYL ESTER

Welcome！

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
+86-23-6139-8061 +86-13650506873
danny@chemdad.com sales@chemdad.com
www.chemdad.com
WhatsApp +86-13650506873