PTIO

PTIO
  • CAS No.:18390-00-6
Other grades of this product :
PTIO Basic information
Product Name:PTIO
Synonyms:2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl)[stablefreeradicalreagentforthesimultaneousdetermin;2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-1-OXYL-3-OXIDE;2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-3-OXIDE-1-OXYL;PTIO;PTIO (2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-3-OXIDE-1-OXYL);PTIO (=2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl) [Stable free radical reagent for the simultaneous determination of NO and NO2 in the atmosphere];[(2-Phenyl-4,4,5,5-tetramethyl-3-oxylato-4,5-dihydro-1H-imidazole-3-ium)-1-yloxy]radical;[(4,5-Dihydro-2-phenyl-4,4,5,5-tetramethyl-1H-imidazole-3-oxide)-1-yloxy]radical
CAS:18390-00-6
MF:C13H17N2O2*
MW:233.29
EINECS:
Product Categories:
Mol File:18390-00-6.mol
PTIO Chemical Properties
Melting point approximate 86℃
storage temp. 2-8°C
solubility soluble in Methanol
form Dark blue solid
color Blue to Dark blue
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
PTIO Usage And Synthesis
DescriptionPTIO is an oxidizing reagent that reacts with nitric oxide to form nitric dioxide and corresponding imino nitroxides. It can be used to assay nitric oxide production when examining nitric oxide synthase inhibitory activity.
Chemical Propertiesblue crystals
UsesPTIO is a nitric oxide (NO) radical scavenger used to inhibit physiological effects of NO.
Uses2-phenyl-4, 4, 5, 5,-tetramethylimidazoline-1-oxyl 3-oxide (PTIO) has been used as a nitric oxide (NO) scavenger.
Synthesis Reference(s)Journal of the American Chemical Society, 90, p. 1078, 1968 DOI: 10.1021/ja01006a053
General DescriptionNitric oxide radical scavenger. Reacts with nitric oxide in a stoichiometric manner without affecting nitric oxide synthase activity. Inhibits the enhanced vascular permeability in solid tumors.
Biochem/physiol ActionsProduct does not compete with ATP.
PTIO Preparation Products And Raw materials

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