Other grades of this product :
| TH1020 Basic information | | Uses |
| Product Name: | TH1020 | | Synonyms: | TH1020;4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2':4,5]thieno[3,2-d]pyrimidine;4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2';TH1020 >=95% (HPLC);4-((4-Benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine | | CAS: | 1841460-82-9 | | MF: | C23H15N7S2 | | MW: | 453.54 | | EINECS: | | Product Categories: | | Mol File: | 1841460-82-9.mol |
| TH1020 Chemical Properties |
| storage temp. | 2-8°C | | form | powder | | color | white to beige |
| TH1020 Usage And Synthesis |
| Uses | TH 1020 is a toll-like receptor 5 (TLR5)/flagellin complex inhibitor. | | Uses | TH1020 has been used to inhibit toll-like receptor 5 (TLR5) in porcine intestinal epithelial monolayer cells and mice. | | Biochem/physiol Actions | TH1020 is a non-cytotoxic non-cytotoxic toll-like receptor 5 (TLR5)/flagellin complex inhibitor. TH1020 selectively prevents flagellin-induced TLR5 signaling without affecting ligands-induced activation of TLR2, TLR3, TLR4, TLR7 or TLR8. |
| TH1020 Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye