Other grades of this product :
| Product Name: | NS309 | | Synonyms: | NS 309; NS-309;1H-Indole-2,3-dione,6,7-dichloro-, 3-oxiMe;6,7-Dichloroindole-2,3-dione 3-oxime;6,7-Dichloroisatin 3-oxime;6,7-Dichloro-3-(hydroxyiMino)indolin-2-one;NS309;NS 309;NS-309;6,7-Dichloro-1H-indole-2,3-dione3-oxime;(Z)-6,7-dichloro-3-(hydroxyimino)indolin-2-one | | CAS: | 18711-16-5 | | MF: | C8H4Cl2N2O2 | | MW: | 231.04 | | EINECS: | | Product Categories: | | Mol File: | 18711-16-5.mol |
| NS309 Chemical Properties |
| Melting point | 190-192℃ | | storage temp. | 2-8°C | | solubility | DMSO: ~22 mg/mL | | form | solid | | color | yellow |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 2 |
| NS309 Usage And Synthesis |
| Uses | NS 309 decreases rat detrusor smooth muscle membrane potential and phasic contractions by activating SK3 channels. | | Biological Activity | Positive modulator of small- and intermediate- conductance Ca 2+ -activated K + channels (SK and IK channels); increases Ca 2+ sensitivity. Displays no activity at BK channels. | | Biochem/physiol Actions | NS309 is a Ca2+-activated IK/SK potassium channel activator. |
| NS309 Preparation Products And Raw materials |
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