Other grades of this product :
| Diethyl butylmalonate Basic information | | Synthesis |
| Diethyl butylmalonate Chemical Properties |
| Melting point | 238 °C | | Boiling point | 235-240 °C (lit.) | | density | 0.983 g/mL at 25 °C (lit.) | | vapor pressure | 1Pa at 20℃ | | refractive index | n20/D 1.422(lit.) | | Fp | 201 °F | | storage temp. | Sealed in dry,Room Temperature | | pka | 13.47±0.46(Predicted) | | form | clear liquid | | color | Colorless to Almost colorless | | Specific Gravity | 0.975 (20/4℃) | | Water Solubility | 330mg/L at 20℃ | | Merck | 14,1576 | | BRN | 608785 | | LogP | 3.4 at 23℃ | | CAS DataBase Reference | 133-08-4(CAS DataBase Reference) | | NIST Chemistry Reference | Diethyl butylmalonate(133-08-4) |
| Safety Statements | 24/25 | | WGK Germany | 1 | | HS Code | 29171990 |
| Diethyl butylmalonate Usage And Synthesis |
| Synthesis | Diethyl malonate is mixed with sodium ethoxide, and then chlorobutane is added to form the reaction. The crude product is separated and recovered ethanol, washed and dehydrated to obtain Diethyl butylmalonate. | | Chemical Properties | CLEAR COLOURLESS LIQUID | | Uses | Diethyl butylmalonate is used as a reagent in the synthesis of 2,5-dihydropyrrole formyl hydroxyamino derivatives as peptide deformylase inhibitors against drug-resistant bacteria. | | Synthesis Reference(s) | Organic Syntheses, Coll. Vol. 1, p. 250, 1941The Journal of Organic Chemistry, 44, p. 3492, 1979 DOI: 10.1021/jo01334a009 | | General Description | Diethyl malonate (DEM) undergoes alkylation by ethyliodide, which is used to study the phase transfer catalysis (PTC) technique. | | Flammability and Explosibility | Notclassified |
| Diethyl butylmalonate Preparation Products And Raw materials |
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