Other grades of this product :
| PF-06700841 tosylate Basic information |
| Product Name: | PF-06700841 tosylate | | Synonyms: | PF-06700841 tosylate;((S)-2,2-difluorocyclopropyl)(3-(2-((1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone;PF 6700841;PF-06700841; PF 06700841; PF06700841; PF-6700841; PF 6700841; PF6700841; PF-06700841 TOSYLATE SALT;PF6700841;PF-6700841;CS-2861;((S)-2,2-difluorocyclopropyl)((1R,5S)-3-(2-((1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone | | CAS: | 1883299-62-4 | | MF: | C18H21F2N7O | | MW: | 389.4 | | EINECS: | | Product Categories: | api | | Mol File: | 1883299-62-4.mol |
| PF-06700841 tosylate Chemical Properties |
| Boiling point | 637.1±65.0 °C(Predicted) | | density | 1.63±0.1 g/cm3(Predicted) | | storage temp. | room temp | | form | powder | | pka | 7.28±0.10(Predicted) | | color | white to beige |
| PF-06700841 tosylate Usage And Synthesis |
| Uses | PF-06700841 tosylate salt has been used as an inhibitor of Janus kinase1 (JAK1) to study its therapeutic effect on the adjuvant induced arthritis (AIA) rat model. It has also been used as an inhibitor of interferon-α/β receptor alpha chain (IFNAR1) signaling adaptor tyrosine kinase (2TYK2) in mice. | | Biochem/physiol Actions | PF-06700841 prevents IL-23 (interleukin 23) signaling through TYK2 (Tyrosine-protein kinase 2)/JAK1 (Janus kinase 1) inhibition. |
| PF-06700841 tosylate Preparation Products And Raw materials |
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