Other grades of this product :
| Product Name: | MAFP | | Synonyms: | 5Z,8Z,11Z,14Z-EICOSATETRAENYL-PHOSPHONOFLUORIDIC ACID, METHYL ESTER;(5Z,8Z,11Z,14Z)-5,8,11,14-EICOSATETRAENYL-METHYL ESTER PHOSPHONOFLUORIDIC ACID;MAFP;MAPF;METHYL-5Z,8Z,11Z,14Z-EICOSATETRAENYL ESTER PHOSPHONOFLUORIDIC ACID METHYL ACETATE;METHYL ARACHIDONYL FLUOROPHOSPHONATE;METHYLPHOSPHONOFLUORIDIC ACID 5,8,11,14-EICOSATETRAENYL ESTER;(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenylmethylester | | CAS: | 188404-10-6 | | MF: | C21H36FO2P | | MW: | 370.48 | | EINECS: | 201-185-2 | | Product Categories: | Cannabinoid receptor;Fatty Acid Derivatives & Lipids, inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals | | Mol File: | 188404-10-6.mol |
| RTECS | TA8108000 | | Fp | -16 °C | | storage temp. | -70°C | | form | methyl acetate solution | | Sensitive | Air Sensitive |
| Uses | (all-Z)-5,8,11,14-Eicosatetraenylphosphonofluoridic Acid Methyl Ester, is a cannabinoid CB1 receptor and fatty acid amide hydrolase inhibitors. | | Biological Activity | Potent, irreversible inhibitor of fatty acid amide hydrolase (FAAH, anandamide amidase), the enzyme responsible for anandamide hydrolysis (IC 50 = 2.5 nM). Also binds irreversibly to CB 1 receptors (IC 50 = 20 nM). | | Biochem/physiol Actions | MAFP is a selective, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic phospholipase A2, but not secretory phospholipase A2. MAFP is also a potent acetylcholinesterase inhibitor. |
| MAFP Preparation Products And Raw materials |
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