Palmitoyl-L-Carnitine Chloride

Palmitoyl-L-Carnitine Chloride
  • CAS No.:18877-64-0
Other grades of this product :
Palmitoyl-L-Carnitine Chloride Basic information
Product Name:Palmitoyl-L-Carnitine Chloride
Synonyms:O-PALMITOYL-L-CARNITINE CHLORIDE;PALMITOYL-L-CARNITINE CHLORIDE;Palmitoyl-L-carnitine hydrochloride;(R)-[3-carboxy-2-[(1-oxohexadecyl)oxy]propyl]trimethylammonium chloride;HEXADECANOYL-L-CARNITINE CHLORIDE;1-Propanaminium, 3-carboxy-N,N,N-trimethyl-2-(1-oxohexadecyl)oxy-, chloride, (2R)-;L-Palmitoylcarnitine chloride;1-Propanaminium, 3-carboxy-N,N,N-trimethyl-2-((1-oxohexadecyl)oxy)-, chloride, (R)-
CAS:18877-64-0
MF:C23H46ClNO4
MW:436.07
EINECS:242-642-6
Product Categories:
Mol File:18877-64-0.mol
Palmitoyl-L-Carnitine Chloride Chemical Properties
Melting point 168-172 °C(lit.)
storage temp. -20°C
solubility H2O: 25 mg/mL with heat or sonication
form powder
color white
BRN 4071005
CAS DataBase Reference18877-64-0
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
3-10
HS Code 2923900090
MSDS Information
ProviderLanguage
SigmaAldrich English
Palmitoyl-L-Carnitine Chloride Usage And Synthesis
Chemical PropertiesWhite crystalline powder
UsesPalmitoyl-L-carnitine Hydrochloride is a long-chain fatty ester of carnitine which is accumulated and released into the circulation, in fatty-acid oxidation defects. Pattern of Lauroyl-L-carnitine can be diagnostic for a number of ?-oxidation defects.
UsesPalmitoyl-L-carnitine chloride has been used as acylcarnitine in treating cardiomyocytes for the induction of reactive oxygen species (ROS).
Biochem/physiol ActionsLong-chain acylcarnitine and well-known intermediate in mitochondrial fatty acid oxidation. Modifies myocardial levels of high-energy phosphates and free fatty acids in the heart. Increases erythroid colony formation in culture. Reduces surface negative charge of erythrocytes and myocytes. Reported to affect currents and inhibit endothelium-dependent relaxation induced by acetylcholine and substance P in a dose-dependent manner by suppressing the intracellular calcium signal transduction in endothelial cells. Inhibits the Na/K pump current but has no effect on the intracellular calcium current in guinea pig ventricular cells. However, like oubain, it reversibly depolarizes the resting membrane, decreases action potential duration, and increases the amplitude of myocyte contractions.
Palmitoyl-L-Carnitine Chloride Preparation Products And Raw materials

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